Evoking of Hypoalgesia effect after of 20 exercise sessions with controlled intensity simultaneous to the Methadone in the addicts

Aim and Pain is one of the factors that produce after of decrease or opiates stop. The purpose of this study was to determination the effect of exercise training on evoking of Hypoalgesia effect subsequent of increased BEND levels in the addicts. Methods and Materials: In this study، 20 male addicts (20-33 years old) were selected after public call and divided into drug supplement (N=10) and exercise -drug supplement (N=10) groups. The first group was performed exercise training to intensity of 70-75 percent of VO2max for twenty sessions (5 sessions per week and for 45 to 55 minutes in each session). They also was consumption 10 milligrams Methadone. The second group only was consumption 10 milligrams methadone daily. After it we survey β- Endorphin levels and hypoalgesia due to mechanical pain and pain due to decrease and increase of temperature. Statistic analysis was shown that the amounts of BEND significantly increase in both groups (P<0. 05). Also، the first group significantly enhanced status of hypoalgesia in all of painful stimulus (P<0. 05). Presumably method of exercise-drug supplement is better for decrease and management of pain in addicts.