The aim of this study was to examine the effectiveness of psychotherapy based on acceptance and commitment therapy (ACT) on the subscales of marital satisfaction; overall satisfaction, religious orientation, relations with children, sex, occasional conflicts, interpersonal conflicts and arrogance, by single case study in the spouses of veterans with spinal cord injuries. Participants completed Enrich marital satisfaction questionnaire at baseline (3 to 6 weeks), during six session’s psychotherapy and the two-month follow-up. Analysis method of charting and visual analysis of the results showed that the (ACT) is an effective therapeutic approach to 4 marital satisfaction subscales but second and third participant didn’t show any improvement.. Considering the above, (ACT) is an effective therapeutic approach to overall satisfaction, occasional conflicts, relations with children and interpersonal conflicts.