Serological Survey of Toxoplasmosis in Pregnant Women

Background and Toxoplasmosis is an infection caused by an intercellular protozoan called Toxoplasma gondii. Toxoplasma has global expansion and its prevalence is different in regions according to geographical conditions, habits and history of contact with cats. The present study determined the seroepidemiology of toxoplasma in pregnant women attending health centers in two cities in north of Iran. In this cross-sectional study, 289 pregnant women who referred to health centers in Ramsar and Tonekabon were randomly selected. After the debriefing questionnaire, blood samples were taken from the subjects. Then IgG and IgM antibodies against T. gondii were examined by ELISA method. Finally the data was analyzed in SPSS. Positive IgG and IgM anti-Toxoplasma antibody were found in 170 (58.8%) and 7 (2.4%) expectant mothers, respectively. Among the participants four (1.4%) were positive for both IgM and IgG and 116 (40.1%) were negative for both types of antibodies. There was no significant relation between the possible risk of T. gondii infection and pregnant women’s place of living, educational level, age, occupation, exposure to cats, and the consumption of raw meat. This study demonstrates a high prevalence of Toxoplasma among pregnant women in Ramsar and Tonekabon. Hence, more training are necessary to raise awareness especially in pregnant women