The Relationship between Eating Disorders and ICAM-1, E-selection and Ghrelin Resting Level in Overweight People

There is an agreement that eating disorder is related to psychological characteristics and on the other hand, level of ghrelin hormone, Intercellular adhesion molecule-1 (ICAM-1) and E-selection also change during eating disorders. We aimed to study the relationship between eating disorders and rest levels, ICAM-1, E-selection, and ghrelin hormone in obese people. In this quasi-experimental study, 120 obese men (25-30 years old) were purposefully selected. Then the data about their eating disorders gathered with eating attitudes test (EAT-26) questionnaire. In the next phase in the rest condition and after overnight fasting, blood samples are collected for measurement of rest levels, ICAM-1, E-selection, and ghrelin hormone. Finally the data were analyzed with appropriate statistical tests in SPSS version 18. Mean and deviation of rest levels, ICAM-1, E-selection, and ghrelin hormone were respectively 3064.19, 61.5±19.7, and 2.5±1.5 and there was not any statistical significance relationship between eating disorders ICAM-1, E-selection, and ghrelin hormone in obese men (P<0.05). According to our results, the prevalence of eating disorders can be a reason other than rest Levels, ICAM-1, E-selection, and ghrelin hormone.