Visualization and Analysisof Nano-Manipulation in Liquid Environment with Atomic Force Microscopy

This paper focuses on a theoretical analysis of an AFM based nano-manipulation in liquid environment. To achievethis goal, major forces in liquid environment were reviewed and the of manipulation processes was modelled by introducing the effect of intermolecular forces and hydrodynamic forces. Dynamic behaviour of pushing a gold nanoparticle of 50-nm radius on a silicon substrate at a velocity of 100 nm/s was investigated. A virtual reality user interface was also implemented and evaluated in liquid environment so that the users can get a senseof forces. The results show that, in comparison to air, the required forces and time are increased by 2 and 6.5%, for sliding and 2 and 4.3% for rolling in liquid environment. Furthermore for various submerged lengths of the cantilever in water, forces and time value are varied 8 and 10.5% respectively.Based on the simulation a result, sliding occurs in nominal values and critical forces and manipulation time in liquid environment increases over the values. For biologicalmanipulation purposes liquid environment is superior in comparison to air and the obtained results are verified by existing experimental.