Evaluation of Amniotic Membrane Efficacy as Biologic Dressing for the Improvement of Donor Site in Burnt Patients

Introduction & Different methods for dressing of donor site in burnt patients who have similarl pain, limitation of mobility of donor site and local complications such as infection and scar. Amniotic membrane has been used for the improvement of healing in some wounds. Accordingly in this study amnion was used as biologic dressing for the donor site to evaluate it’s efficacy in the improvement of pain, movement score and the risk of local infection. This study was done as a clinical trial over 32 admitted patients in the burn department of the hospital. Amnion was prepared in the elective caesarean section after ruling out any placental site with routine dressing. Then the two sites were compared about the severity of the pain, movement score, infection and time of dressing sloughing. Fourteen patients were women and 18 men. The mean score of pain and movement up to the sixth post operative day respectively was less than the control site. No difference was seen in the infection and dressing slough in the two sites. It seems that the use of amnion for the dressing of donor site probably causes more rapid epithelialization and wound healing and can improve pain and movement score in early post operative days. Accordingly it is expected to need less analgesia and low rate of immobilization associated with the complication of burnt patients after graft and their early discharge.