The Effect of Apple Juice on Antioxidant Enzymes and Lipid Profiles in Orchidectomized Rats
Author(s):
Abstract:
Background
The age-dependent worsening of lipid profiles increased the risk of cardiovascular disease in males. Eating fruits and vegetables is known to be beneficial on lipid profile. Objectives
The objective of this research was to delineate whether drinking daily squeezed apple juice (AJ) modulates lipid profile and antioxidant enzymes in the animal model that gonadectomized. Materials And Methods
In this experimental study, 28 male rats were equally divided among the following 4 groups: group I (control), orchidectomized (ORX), ORX +AJ 10%, and ORX+ AJ 25%. After 60 days of drinking AJ, superoxide dismutase (SOD), alkaline phosphatase (ALP), cholesterol, LDL, HDL and triglycerides in serum were evaluated. Data analyzed by SPSS-16 and computed using one way ANOVA followed by Tukey multiple comparison test. P < 0.05 was statistically significant. Results
In the ORX group compared with the sham group serum SOD and ALP activities decreased (P < 0.05), while serum cholesterol, triglycerides, LDL increased but HDL decreased in ORX groups (P < 0.05). In contrast to the ORX group, drinking AJ decreased (P < 0.05) concentration of LDL, TG and cholesterol in the serum. AJ also increased (P < 0.05) serum HDL, SOD and ALP activities compared with the ORX group. Conclusions
Drinking AJ prevented oxidative stress by elevating serum antioxidant enzymes.Keywords:
Antioxidants , Cholesterol , Malus , Rats
Language:
English
Published:
Zahedan Journal of Research in Medical Sciences, Volume:17 Issue: 3, Mar 2015
Page:
1
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