Frequency of Toxoplasma Infection Among Pregnant Women and Their Newborn in Kashan, Iran

Congenital toxoplasmosis (CT) is the result of maternal infection if acquired during gestation, an infection that most often is clinically unapparent. This study was conducted to determine acute and chronic toxoplamosis in pregnant women and its complications in newborn. Patients and In this cohort study, 798 pregnant women were tested for Toxoplasma IgG/IgM by ELISA. PCR and IgM were performed on 4 newborns of acute and 5 chronic maternal infections; they were followed for 1 year. Data were analyzed by SPSS-11.5 and χ2 test. Five (0.63%) and 341 (42.7%) were positive for acute and chronic infections. A 400 bp band was seen in 3 newborns of acute maternal infections. The incidence of neonatal toxoplasmosis was 3.7 per 1000. Only one neonate of the acute maternal toxoplasmosis had jaundice. The rate of maternal and neonatal toxoplasmosis, were higher than the world. Jaundice was only sign in newborn with Toxoplasma gondii infection.