Despair is one of the negative emotional states in human that many factors، including-mindedness، not believing in God، evil`s temptations، false hopes، failures، suspicion، and… lead it to emerge and has dangerous and irreversible consequences. Many wise and valuable remarks of Imam Ali (AS)، in the book Nahjolbalaghe، contain how to act and provide guidelines in confronting and managing this emotional state. It also includes techniques on how to stimulate positive emotions in humans for the treatment and eradication of despair. The main strategies and practices that Imam Ali (AS) have used to stimulate positive emotions in people in order to treat despair are patience، trust in God، prayer and invocation، optimism and…