Cervical Artery Dissection: A Review of the Epidemiology, Pathophysiology, Treatment, and Outcome
Author(s):
Abstract:
Context: Cervical artery dissection (CAD) is a common cause of stroke in young adults. There is controversy over whether anticoagulation is superior to antiplatelet therapy in preventing stroke in patients with CAD, although meta-analyses to date have not shown any difference between the two treatments..Evidence Acquisition: We performed a PubMed search using each of the keywords: “Cervical artery dissection”, “Dissection”, “Carotid dissection”, and “Vertebral dissection” between January 1st, 1990 and July 1st 2015. We identified evidence-based peer-reviewed articles, including randomized trials, case series and reports, and retrospective reviews that encompass the epidemiology, clinical manifestations, pathophysiology, treatment, and outcome of cervical artery dissection..
Results
This paper highlights the mechanisms of cervical artery dissection and stroke in patients with dissection as well as the natural history and treatment..Conclusions
Given the relatively rare incidence of this disease, multicenter studies with collaborative effort among stroke centers worldwide should be considered to enroll patients with cervical artery dissection in a randomized trial comparing the two treatments..Keywords:
Language:
English
Published:
Archives of Neuroscience, Volume:2 Issue: 4, Oct 2015
Page:
2
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