Rubeosis Irides Complicating Acquired Astrocytoma of Solitary Optic Nerve Head a Clinicopathologic Case Report

To report a rare case of large vascularized astrocytoma on optic disc. Case Report: A 12-year-old boy with history of decreased vision in the left eye since 5-6 months ago was referred to the ocular oncology service at Rassoul Akram Hospital with provisional diagnosis of retinoblastoma. On examination, visual acuity was counting fingers at 50 cm, and a 3+ relative afferent pupillary defect response as well as an exodeviation was evident in the left eye. Fundus examination of the left eye revealed a large yellow-white mass with superficial vessels overhanging the optic disc. Right eye slit lamp exam and funduscopy were unremarkable. No clinical manifestation of tuberous sclerosis was found. Orbital CT scan, MRI and ultrasonography of the globe was done. Enucleation was performed because of the development of iris neovascularization and progressive enlargement of the tumor. Histologic exam confirmed the diagnosis of astrocytoma.