Evaluation of doses in the Wernicke and Broca's areas using two different technique in patients with right frontal glioblastoma multiforme
Author(s):
Abstract:
Background
Brocas and Wernickes areas, which are important language areas of brain, are commonly irradiated in patients with right frontal lobe glioblastomamultiforme (GBM). We aimed to compare two different treatment planning techniques in terms of the doses in the Brocas and Wernickes areas for the patients with right frontal GBM.Materials And Methods
Two different treatment planning techniques of right frontal GBM were generated for Rando phantom: two field technique using parallel opposed beams and three field techniques. Both plans were compared for doses in planning target volume (PTV), Brocas and Wernickes areas. Additionally to test the accuracy of treatment planning system (TPS) dose calculation thermoluminescent dosimeters (TLD) were used.Results
The three field technique allowed the lower doses in the Brocas and Wernickess areas. The doses calculated in the Brocasand Wernickes areas were 0.98% ± 0.03 and 0.09% ± 0.06 of the isocenter dose with three field and 1.06% ± 0.04 and 0.133% ± 0.03 of the isocenter dose with two field techniques respectively. When the doses measured by TLD and calculated with TPS were compared the differences were 3.23% and 2.92 % for Brocas area, and 4.12 % and 3.95% for Wernickes area for two field and three field techniques respectively.Conclusion
There was a good agreement between TPS and TLD calculations for both techniques. Three field techniques seem to be more advantageous than two field technique with respect to doses of Brocas and Wernickes areas. However this finding should be clarified with further clinical studies.Keywords:
Language:
English
Published:
International Journal of Radiation Research, Volume:14 Issue: 1, Jan 2016
Pages:
43 to 50
magiran.com/p1521005
دانلود و مطالعه متن این مقاله با یکی از روشهای زیر امکان پذیر است:
اشتراک شخصی
با عضویت و پرداخت آنلاین حق اشتراک یکساله به مبلغ 1,390,000ريال میتوانید 70 عنوان مطلب دانلود کنید!
اشتراک سازمانی
به کتابخانه دانشگاه یا محل کار خود پیشنهاد کنید تا اشتراک سازمانی این پایگاه را برای دسترسی نامحدود همه کاربران به متن مطالب تهیه نمایند!
توجه!
- حق عضویت دریافتی صرف حمایت از نشریات عضو و نگهداری، تکمیل و توسعه مگیران میشود.
- پرداخت حق اشتراک و دانلود مقالات اجازه بازنشر آن در سایر رسانههای چاپی و دیجیتال را به کاربر نمیدهد.
In order to view content subscription is required
Personal subscription
Subscribe magiran.com for 70 € euros via PayPal and download 70 articles during a year.
Organization subscription
Please contact us to subscribe your university or library for unlimited access!