Effect of Omega-3 Fatty Acids on Testosterone Plasma Level in Wistar Rat

High prevalence of infertility and many related problems has become a big problem for economy and healthy. This study is to determine the effect of dietary omega-3 based on hypothalamic–pituitary–gonadal axis (HPG) activity and testosterone plasma level in adult male adult wistar rat.
This experimental study was conducted on 40 adult male wistar rats. Animals were with an average weight of 150±20 gr. They divided into five groups (n=8), including the control group, saline group and experimental group of minimum , average and maximum in which consumed dietary including omega-3, 0.25 and 0.5 and 0.75 mg/kg dose the 29 days. The blood was take from the heart of animals. Using Radioimmunoassay methods, testosterone and LH levels were measured. In this study effects of dietary omega-3 on testosterone secretion level in experimental groups, was compared with saline and control groups.
The results of a compared LH and testosterone level with the control group (0.167±0.02 and 0.182±0.02) and all experimental groups, particularly at the maximum dose (0.654±0.09and 0.584±0.12 respectively), showed a significant increase.
It was shown that the increase in omega-3 plasma levels of in the experimental group led significantly increase in the testosterone and LH level. This study showed that consumption of Omega-3 oils, significantly increase plasma levels of testosterone and LH hormone.