Antibiotic resistance pattern of Staphylococcus epidermidis strains isolated from a referral hospital in Isfahan

Staphylococcus epidermidis is a normal flora of human in different parts of the body which is known as an opportunistic pathogen in nosocomial infections. The aim of this study was to determine the antibiotic resistance patterns of S. epidermidis strains isolated from clinical samples in a referral hospital in Isfahan.
In this study, total of 107 S. epidermidis strains isolated from different clinical samples in a referral hospital in Isfahan, during 2015. All isolates were identified at the species level using standard biochemical tests and PCR method by species specific primers. Antibiotic susceptibility of strains to 9 antibiotics was determined by disc diffusion method according to the guideline of Clinical and Laboratory Standards Institute (CLSI).
The highest level of resistance was observed to erythromycin and also high resistance to clindamycin, cefoxitin, tetracycline and trimethoprim/sulfamethoxazole, was determined. All S. epidermidis strains sowed susceptibility to linezolid and quinupristin-dalfopristin.
Prevalence of resistance to broad spectrum of first and second lines antibiotics for treatment of S. epidermidis infections, indicating spread and distribution of these strains in this hospital in Isfahan. Lack of attention to antibiotic resistant S. epidermidis strains, which are members of human microbiota, could be an urgent for public health.