Immunization of Shrimp by Irradiated Vibrio Paraheamolyticus Against White Spot Syndrome Virus

Shrimp farming industry is of significant importance to the economy, particularly in the south area of Iran. However, this industry faces with various challenges such as viral and bacterial disaeses. The losses due to Vibriosis and white spot syndrome in shrimp are examples of the issues. Therefore, taking into account the control of the diseases outbreaks, this investigation was carried out to study the immunity of Vibrio radio-antigen (inactivated whole-cell bacteria by the gamma irradiation method) against the white spot syndrome virus (WSSV) in Litopeaneus vannamei. The results showed that the treatment with the Vibrio radio-antigen caused an immune response against live WSSV in shrimp via significant decreasing of mortality in the immunized shrimp groups, in comparison with the positive control group after challenge with the live WSSV (P<0.05). The results of this investigation are potentially useful for future studies in production of radio-vaccine and adjuvant of Vibrio paraheamolyticus.