Association of Liver Enzymes with 10-year Cardiovascular Disease Risk: A Population-Based Study

The association between liver enzymes and cardiovascular disease (CVD) was previously demonstrated. This study investigated the possible association between liver enzymes and the 10-year risk of cardiovascular events..
The study consisted of 3199 subjects. Two risk-assessment methods, the framingham risk score (FRS) and American college of cardiology and American heart association (ACC/AHA) tools, were used to predict 10-year cardiovascular risks. The association between liver enzymes and ≥ 7.5%, ≥ 10%, and ≥ 20% 10-year CVD risks were evaluated..
In the multivariate analysis, alkaline phosphatase (ALP) was significantly associated with 10-year CVD risks in both men and women (P While ALP exhibited an independent positive association with 10-year CVD risks in both genders, ALT showed an inverse association with10-year CVD risks in men and with some levels of risks in women..