Comparison adding intraarticular growth hormone to platelet rich plasma under ultrasound guidance in knee osteoarthritis

Several methods have been proposed for the treatment of knee osteoarthritis pain like as platelet rich plasma. The aim of this study is to compare adding intraarticular growth hormone to platelet rich plasma under sonographic guidance on joint function in knee osteoarthritis .
Fifty four patients with knee osteoarthritis divided into two equally groups including 27 individuals. Injectate in first group (P) was 5 ml of platelet rich plasma and in second group (PS) 4 units of growth hormone (Somatropin) added to platelet rich plasma. Intra-articular injection was done at two times; the onset of study, and one month later. Demographic data were recorded. Knee joint function based on WOMAC Score at the time 0, 1 and 2 month later and complications were evaluated.
WOMAC Score in both groups has been significantly reduced after injections (P=0/476) WOMAC score reduction in second group (PS) at month 1 was significantly higher than the first group (P) but in month 2, the difference between two groups was not significant. (P=0/476) .No complication was observed.
Adding intraarticular growth hormone to platelet rich plasma can be effective in knee joint function of osteoarthritis patients at short time basis.