the effect of pulmonary ventilation during cardiopulmonary bypass)CPb(on pulmonary outcomes and complications after coronary artery bypass graft

Aim and Despite improved techniques of cardiopulmonary bypass and postoperative care, pulmonary dysfunction after CABG is still a major cause of postoperative morbidity. Different methods of pulmonary ventilation have been used for lung protection. But has not definite conclusions about the effects of these methods. The aim of this study was determining the effect of pulmonary ventilation during cardiopulmonary bypass on postoperative outcomes and pulmonary complications.
Methods and Materials: This experimental study was done on 74 Patients undergoing elective coronary artery bypass graft surgery with convenience sampling. The patients were randomly divided to two groups: Mechanical ventilation during cardiopulmonary bypass )case( and non ventilation )control(. Physiologic variables during and after surgery and post operative outcomes and pulmonary complications were assessed. The data was analyzed by SPSS 16.
Findings: Atelectasis after tracheal extubation in case group was less than control group )p=0.019 Odds Ratio= 5.8(. There were no statistical differences in incidence of pneumothorax and pleural effusion after surgery, as well as, tracheal extubation time, length of stay at ICU and in hospital between two groups )p> 0.05(.
Mechanical ventilation during cardiopulmonary bypass is effective on decrease atelectasis after surgery. Although most of the published studies have no evidence of lung protection, it is need more studies for best strategy for diminish pulmonary complications after cardiac surgery.