Reliability, Validity, Factor and Discrimination Power Analysis of Young Mania Rating Scale among Unipolar, Bipolar Depression and Healthy People

Unipolar depression disorder is different from bipolar depression disorder base on both phenomenology and biology. Discrimination of these two disorders in depression phase is a little difficult needing precise interview and suitable instrument. The goal of this study was to determine reliability, validity and factor and discrimination power analysis of young mania rating scale (YMRS).
Subjects and Three hundred and sixty seven people (120 bipolar depression disorder, BMD, 126 major depression disorder, MDD and 121 healthy people) from Medical University of Isfahan’s clinical centers and private clinics were participated in this study. We used Young Mania Rating Scale, Bipolar Depression Rating Scale, Hamilton Depression Rating Scale and Beck Depression Inventory for gathering data, then analyzed them using Pierson Correlation, factor analysis and discrimination power analysis.
YMRS had a high internal consistency (a=0.82) in Iranian population and it also showed a high concurrent validity with mixed subscale of BDRS (r=0.74.5). Factor analysis showed three factors named hyperactivity, high risk behavior and prognosis based on DSM-5 criteria for BMD. The best clinical cut of point was 7.5 with sensitivity of 62.5% and specificity of 89% to distinguish unipolar depression disorder from bipolar depression disorder.
Persian version of YMRS has good psychometric characteristics and has an acceptable power analysis for discrimination between BMD from MDD.