The Relationship of Coronary Heart Disease and Valvular Heart Disease in Patients with Stable Angina

Valvular heart disease as a public health problem in developing countries. Studies reported a lower incidence of coronary artery disease (CAD) among patients with valvular heart disease. The relationship of valvular heart disease and coronary artery disease is still unknown. The aim of this study was to evaluate the association between valvular heart disease and coronary artery disease in patients with stable angina.
This was a case-control study on 1062 patients with stable angina undergone angiography for certain elective indication in Shahid Chamran hospital, Isfahan University of Medical Sciences (IUMS), Iran, from September 2011 to September 2016. Besides, the echocardiography was evaluated within 6 months before and 6 months after the coronary angiography. Then relationship between coronary artery disease and having valvular heart disease was assessed.
Findings: In this study, 1062 patients with mean age of 61.67 ± 11.38 years were evaluated that 64% of them were men. About 61.3% had coronary artery disease and 33.9% had valvular heart disease. Patients with coronary artery disease were at lower risk for experiencing valvular heart disease. Patients with mitral stenosis or mitral regurgitation, aortic stenosis or regurgitation, and those with tricuspid valve regurgitation were less likely to have coronary artery disease. 22.0% of patients with coronary artery disease had one vessel involvement. In addition, patients with two vessels involvement had less valvular heart disease than patients with one or three vessels involvement.
Patients with coronary artery disease were less likely to develop heart valve disease. Patients with coronary artery disease showed milder valvular heart disease.