The effect of commercial probiotic formulations on reduction of Bisphenol-A in-vitro

Bisphenol-A (BPA) is an industrially important compound used in the production of polycarbonates, epoxy resins and thermal papers in many chemical manufacturing plants throughout the world. So, this dangerous chemical toxin may be taken up via the diet and have adverse effects on human health. On the other hand, inducing beneficial bacteria is an effective way to improve the biosafety and health level. The induction process can be done by supplements containing large amounts of probiotics. Combination of compatible probiotic strains from different species may improve synergistic relation among bacteria and increase the effectiveness of treatment. In this study we try to investigate and quantify the effect of commercial probiotic formulations exist in Iran pharmaceutical market on reduction of bisphenol A. For this purpose, the amount of environmental BPA was measured during a 24-hour treatment with the mixture of probiotic strains. Our results showed a significant drop in BPA concentration compared with the toxicity of the control group. The experimental framework was arranged in a way to determine the most efficient strains. Almost all groups could reduce about 80% of BPA in the first hour. Also, these results suggest that regular usage of probiotic supplementation with special mixture of strains can suppress the harmful effects of BPA.