Gender-Related Differences in Presentation and Outcome of Acute Type a Aortic Dissection

Although acute type-A aortic dissection (AAOD) is more common in males, the course of the disease may differ in females.
We aimed to investigate the gender-related differences in patients with AAOD with regard to clinical presentation, short-term and long-term mortality.
Patients and Medical records of 192 patients with a confirmed diagnosis of AAOD in a University Heart Center from March 2004 through October 2015 were evaluated. Clinical information, hospital mortality, and long-term survival were explored with regard to gender. Propensity matching was performed to adjust for baseline differences. Kaplan-Meier survival analysis was used to determine the impact of gender on long-term mortality.
Among 192 patients, 71 (37.0%) were females. The women were older (65.7 ± 13.8 vs. 53.9 ± 15.1 years, P In patients admitted with AAOD, there was no gender-related differences in clinical presentation and type of management. Similarly, hospital and long-term mortality did not differ with regard to gender.