Comparison of Residual Triple Antibiotic Paste, Propolis and Calcium Hydroxide on Root Canal Walls in Natural Open Apex Teeth: An In Vitro Study

Endodontic therapy is challenging in open apex teeth. One of these problems is the residue of medicaments on root canal walls. The aim of this study was to evaluate the amount of residual materials on canal walls after the use as medicaments within natural open apex teeth.
Methods and Materials: A total of 45 human extracted single-rooted premolars with open apices were selected. After cutting off the crowns, root canals were gently instrumented using #40 files and irrigated with 0.5% sodium hypochlorite. The samples were randomly divided into three groups: calcium hydroxide (CH), triple antibiotic paste (TAP) and propolis (PP). In these groups, CH, TAP, or PP were placed into the canals, respectively. The samples were then restored with temporary fillings. After one week, instrumentation was again performed as mentioned above. The samples were longitudinally cut and scanned and the remaining material in both halves was evaluated using computer software. One-way ANOVA was used to compare the average paste level remaining on the canal walls.
The residual amount of CH on the canal walls was significantly higher than that of PP (P=0.001). The residual amount of CH was higher than TAP but this difference was not significant (P=0.144); the residual amount of TAP was higher than PP but this difference was not significant, either (P=0.094).
PP is superior to CH and TAP in terms of removability from the root canal system within open apex teeth.