Comparative Evaluation of Ocular Wavefront Characteristics in Bilateral Keratoconus Patients with Unilateral Corneal Vogt's Striae

The aim of this study was to evaluate and compare ocular wavefront characteristics in bilateral keratoconus (KCN) patients with unilateral corneal Vogt`s striae.
In this prospective cross-sectional contralateral eye study, fifty patients diagnosed with bilateral KCN with unilateral corneal Vogt`s Striae with age ranged 20-38 years were recruited. All subjects underwent a comprehensive ophthalmic examination, including monocular uncorrected distance visual acuity, monocular corrected distance visual acuity, refraction (converted to Vetcor component), slit lamp biomicroscopy, Scheimpflug-based tomography (Pentacam HR, Oculus, Germany), and placido disc-based topography (TMS-4, Tomey, Erlangen, Germany). Following pupil dilation, ocular wavefront aberrations were measured by means of iTrace (Tracey Technologies, Houston, Tx). All the ocular wavefront aberrations were evaluated and compared between the KCN eyes with and without Vogt`s striae. Wilcoxon signed rank test was used to compare the parameters.
P-value A total of 50 bilateral KCN patients with the mean age of 27.43±5.46 years were enrolled in this study. The results of this study showed that there were significant differences in the sphere, cylinder, spherical equivalent, uncorrected distance visual acuity, corrected distance visual acuity, and J0 (P The iTrace measurements for ocular wavefront showedasignificant increase in the majority of ocular HOA and LOA aberrations in the keratoconic eye with corneal Vogt`s striae compared to the eyes without Vogt`s striae. These results should be noticed in clinical evaluations and treatments of KCN patients with Vogt`s striae.