Synthesis of ZnS:Mn Nanoparticles And Investigaton of Its Ability to Produce Reactive Oxygen Species

Today, semiconductor nanoparticles have attracted much attention in nano-medicine branches. In this study, the ability of the ZnS:Mn nanoparticles to produce reactive oxygen species including radical hydroxyl were investigated and also preparation method of these nanoparticles was reported. ZnS:Mn nanoparticles were synthesized using co-precipitation method. Excitation of nanoparticles was done by UV radiation. The formation and structure of nanostructures was investigated by XRD, SEM and PL analysis. The PL emission spectrum of the ZnS:Mn nanoparticles shows two main peaks in wavelength of 444 and 587 nm. The size of ZnS:Mn nanoparticles was obtained at about 24 nm using XRD result which it is in agreement to SEM and TEM images. According to the decrease in absorption intensity of methylene blue detector in irradiation alongside prepared nanoparticles, it can be said that ZnS:Mn nanoparticles are able to create hydroxyl radicals. This suggests that ZnS:Mn nanoparticles can be used to cancer therapy in photodynamic therapy method