The effects of spring viremia of carp virus (Carp sprivivirus) on blood biochemical parameters and liver enzymes of the Caspian kutum fry (Rutilus kutum)

In this study, the effects of spring viremia of carp virus (SVCV, Carp sprivivirus) with 104 TCID50 on liver enzymes including alkaline phosphatase, lactate dehydrogenase, alanine aminotransferase, aspartate aminotransferase and blood biochemical parameters containing albumin, urea, fat, cholesterol, protein and glucose of Rutilus kutum were measured. The first clinical symptoms and mortality in intraperitoneal injection and bath trials were observed in 13 and 16 days post-treatment respectively. Liver enzymes in the bath and intraperitoneal injection treatments showed significant differences compared to the control (P<0.05). The highest increase of the liver enzymes except alanine aminotransferase were observed in the bath treatment compared with the intraperitoneal injection. Some blood biochemical parameters including albumin and fat had significant differences in the intraperitoneal injection treatment compared with other treatments (P<0.05). Urea, protein and glucose in the intraperitoneal injection treatments showed significant differences compared to the control (P<0.05.). Cholesterol showed significant differences among different treatments. The highest level of biochemical parameters was observed in intraperitoneal injection treatment. As a result, the SVCV able to make changes in liver enzymes, biochemical parameters and clinical signs, followed by mortality in the Caspian kutum fingerlings.