Magnetic resonance force microscopy (MRFM)

In nanotechnology and molecular biology, researchers are often severely limited by the inability to observe atoms and molecules in three dimensions. Magnetic resonance force microscopy (MRFM) is a kind of scanning probe microscopy which combines the three-dimensional imaging capabilities of magnetic resonance imaging (MRI) with the high sensitivity and resolution of atomic force microscopy (AFM). MRFM uses a micro magnet cantilever to detect the interaction force between a magnetic field gradient and a nucleus spins in a sample surface atoms.