Evaluation of the Impact of Out-of-Axial FOV Scattering Medium on Random Coincidence Rates on Discovery 690 PET/CT Scanner: A Simulation Study

Positron Emission Tomography (PET) imaging is a nuclear medicine imaging technique based on the recording of two photons as coincidence created by positron annihilation.

PET coincidence events include true and unwanted coincidences (random, scattered, multiple coincidences). We modeled the Discovery 690 (D-690) PET scanner using the GATE simulation tool and estimated the effect of the diameter of the scattering medium out of the Axial Field of View (AFOV) on the random coincidence rates.

The validation results indicated that the average difference between simulated and measured data for sensitivity and scatter fraction tests are 5% and 3%, respectively. Moreover, the results revealed that the increasing diameter of the scattering medium out of the AFOV has a direct effect on the random coincidence rates within the Field of View (FOV).

The study concluded that the presence of a scattering medium near the FOV increases the rate of random coincidences.