Catalyst and solvent-free synthesis of β-enaminone derivatives

In this study, the green procedure for synthesis of the β-enaminones is described. The reaction of aromatic amines with β-dicarbonyl compounds under solvent and catalyst-free conditions at 120 °C affords the β-enaminone and β-enamino esters in high-to-excellent yields, in short reaction time, easy separation, work up and purification without need to column chromatography. Also, some new derivatives of β-enaminones were synthesized using this method. The prominent advantages of this new method is operational simplicity, good yields in short reaction times, easy work-up procedures, catalyst and solvent free condition.