Methamphetamine Manufactured from Pseudoephedrine; Both as DoubleEdged Swords

Methamphetamine, or meth, is a potent stimulant that is prescribed for psychiatric conditions such as attention deficit hyperactivity disorder (ADHD) and weight issues. Contrariwise, this agent is more used recreationally for energy boosting and feelings of strength it creates. Pseudoephedrine (PSE) is the key ingredient used to produce methamphetamine. Pseudoephedrine has one less hydroxyl group compared to another commonly used sympathoimetic in cold and allergy products which results in a more lipid soluble molecule and thus more CNS availability. (1)  Methamphetamine has many other names such as “Meth”, “Crystal”, “Speed”, “Crank”, “Chalk”, “Wash”, “Trash”, “Pookie” (2), “Shisheh” or “Glass” in Iran, is considered the second most abused illicit drug. Considerable struggles have been made to lower the supply and demand for recreational drugs. Methamphetamine is of specific importance because of its popularity and crimes outcomes. (3)