Survival Rate of Patients with Squamous Cell Carcinoma of Larynx Undergoing Nonsurgical Treatments and Radiotherapy, From 2003 to 2015
Message:
Abstract:
Background
The incidence rate of head and neck cancer in the world is about 560,000 new cases a year. Larynx cancer is the most common malignancy in head and neck in Iran. The most common head and neck carcinoma is the malignancy of squamous epithelial cells. This study was conducted to determine the survival rate of patients undergoing nonsurgical treatment methods for laryngeal squamous cell carcinoma in Kerman, Iran.
Methods
This retrospective study was conducted on patients with squamous cell carcinoma of larynx following nonsurgical treatment, who were referred to a radiation therapy center in Kerman, Iran, from 2003 to 2015.The likelihood of survival of patients based on the age, sex, stage of disease, non-surgical treatment, laryngeal preservation, as well as survival without progression and recurrence of the disease was determined.
Results
Mean age of the studied patients was 56.56 years. The patients had a mean survival rate of 52.92 months, mean disease free survival rate of 47.60 months and mean progression free survival rate of 11.29 months. The survival rate was higher in patients undergoing RT, followed by those undergoing CCRT and CT-RT (P<0.001). The patients had a one-year disease free survival rate of 69%, a three-year disease-free survival rate of 57% and a five-year disease-free survival rate of 44% and had a one-year progression free survival rate of 13% as well as a three- and a five-year progression free survival rate of 18%.
Conclusion
Overall survival rate was significantly different based on the type of non-surgical treatment, gender and the stage of cancer.
Article Type:
Research/Original Article
Language:
English
Published:
Journal of Kerman University of Medical Sciences, Volume:27 Issue: 1, 2020
Pages:
49 - 59
magiran.com/p2099120  
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