Design and Simulation of a Novel Surface Plasmon Based Bio-Nanosensor for Detection of DNA Hybridization
This paper proposes a novel plasmonic sensor for biological applications such as single-stranded DNA detection that it is simulated and analyzed using the FDTD method. The sensor detects the adsorption of DNA molecules in the sensing solution (PBS) by changes in the reflectance of the structure. The mechanism of this sensor is based on the variation of refractive index with the absorption of different concentrations of molecules. The proposed structure consists of metal (gold/silver)-indium tin oxide (ITO)-graphene and an assay medium. The results showed that the ITO metal oxide layer plays an important role in the sensor parameters. By optimizing the thicknesses of metals (gold and silver), the metal oxide, and graphene, we obtained the maximum sensitivity of 75 deg/RIU for the gold-graphene-analyte structure and the maximum detection limit of 58.33 for the silver-ITO-analyte structure. The structures proposed in this paper outperform those presented in previous works. Thus, the proposed biosensor is able to open a new window for biomolecule detection.
Biosensor , Surface Plasmon , ITO , Graphene , DNA
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Designing and manufacturing of the laboratory optical fiber sensor for detection of the gas pressure by Fabry-Perot method and the investigation of the effect of the polymer material on its sensitivity.
*, Farzad Bashiri, Hamed Moradi
Journal of Applied Electromagnetic, -
Theoretical study of the effect of the layer thickness on the sensitivity of tapered fiber optic sensors
Mohammad Vahedi *,
Journal of Applied Electromagnetic,