Investigating The Relationship Between Gastric Polyp and Dyspepsia in Patients Referring to Taleghani Hospital During 2016-2018

Chronic dyspepsia is a common medical problem in patients referred to internal and gastrointestinal clinics. According to some studies, most pa-tients with dyspepsia suffer simultaneously from gastric polyps. The current study aimed to clarify the association of gastric polyp and dyspepsia in an Iranian population.

A total of 2772 dyspeptic and 1294 non-dyspeptic subjects who referred to the gastrointestinal clinical Ayatollah Taleghani Hospital in Tehran from2016 to 2018 were enrolled in this cross-sectional study. All subjects underwent upper gastrointestinal (GI) endoscopy, and patients with GI malignancy, severe GI bleeding, and history of GI surgery were excluded from the study. Participants were evaluated for age, gender, endoscopic findings, gastric polyp (GP) count, size, and lo-calization, diagnostic methods used for histology, and polyp features. The relationship between gastric polyp and dyspepsia was also evaluated.

In 4066 consecutive upper GI endoscopies in patients with and without dys-pepsia, 129 patients (3.2%) were found to have gastric polyps (GPs).The prevalence of GPs was 3.04% and 3.32% in subjects with and those without dyspepsia, respec-tively. There was no statistically significant relationship between GPs and dyspepsia (p=0.709). Hyperplasic polyp (HP) was the most common pathology in 53.5% and 34.9% of patients with and without dyspepsia, respectively. The most common location for polyps was the gastric antrum (76.7%), and the common size of the polyps was between 5-10 mm in 80.6% of patients.

In the present study, no statistically significant difference was observed in the pathologic findings of gastric polyps in terms of dyspepsia. Hyperplasic polyps (HPs) are the most common type of pathologic stomach polyps, and its prevalence maybe high due to the high frequency of Helicobacter pylori (H. pylori) infection in our country.