Xeroderma Pigmentosum in Children: Report of 4 Cases

Message:
Article Type:
Case Report (دارای رتبه معتبر)
Abstract:

Xeroderma pigmentosum (XP) is a rare genetic disorder inherited in an autosomal recessive pattern. Patients with XP are extremely sensitive to ultraviolet (UV) radiation that leads to defective DNA repair. People with XP often suffer from problems in the eyes, face, neck, and other areas of the body, frequently exposed to sunlight. It is characterized by photosensitivity, dry skin, pigmentary changes of the skin, premature skin aging, and a considerable increase in incidence rates of malignant skin tumors. There is no cure for XP. In this article, we have described four patients from two families, three of whom had malignant skin tumors.

Language:
English
Published:
Journal of Health Scope, Volume:9 Issue: 4, Nov 2020
Page:
11
https://www.magiran.com/p2209725  
سامانه نویسندگان
  • Miri Aliabad، Ghasem
    Corresponding Author (1)
    Miri Aliabad, Ghasem
    Full Professor Department of Pediatric Hematology Oncology, Iran University Of Medical Sciences, Tehran, Iran
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