The Effects of 8 Weeks of Aerobic and Resistance Exercises on Salusins Levels and Inflammatory Indices in Type 2 Diabetic Women

The purpose of this study was to investigate the effects of eight weeks of aerobic and resistance exercise on the levels of alpha and beta salusins, and inflammatory indices in type2 diabetic women. For this purpose, 45 volunteer participants were randomly assigned to the three groups of 15, including aerobic exercise, resistance exercise, and control. Resistance and aerobic exercises were performed three times a week for eight weeks with a gradual progressive manner. Resistance training consisted of 8-12 repetitions at 60-70% of 1RM, and aerobic training consisted of 30-50 minutes of running on a treadmill at 65-75% of maximum heart rate. Before and after the intervention period, serum levels of alpha and beta salusins, malondialdehyde and IL-1β were measured. The results showed significant decrease in salusinβ levels in both aerobic (P=0.015) and resistance (P=0.019) groups. In the other side, the levels of salusinα were significantly increased in aerobic (P=0.034) and resistance (P=0.012) groups. In addition, the IL-1β levels were significantly decreased in both aerobic (P=0.034) and resistance (P=0.041) groups. However, the levels of malondialdehyde had no significant changes in any group. The level changes of salusinα, salusinβ, and IL-1β were not significant between the aerobic and resistance groups. According to the results of the present study, performing eight weeks of resistance or aerobic training can positively affect the levels of salusinα, salusinβ and IL-1β in women with type2 diabetes.