Correlation Between Breast Tumor Size and Lymph Node Involvement in Patients Referring to the Pathology Department of Rasoul Akram Hospital in Iran

 Breast cancer has the highest mortality rate, second to gastric cancer, among Iranian women and is one of the most common cancers in the world. The incidence of breast cancer in women is increasing gradually. Meanwhile, ductal breast carcinoma experiences more increases than other malignancies and is one of the most important health problems.

 This study aimed at evaluating women with ductal breast carcinoma because of the significance of pathological factors and their association with breast cancer progression.

 This retrospective study was conducted using data of ductal breast carcinoma women during the years 2018 and 2019. In this cross-sectional study, demographic data (age, sex, and pathology of breast mass) of 50 patients referring to Rasoul Akram hospital (Tehran, Iran) were gathered. Then, the data were analyzed by SPSS 26 software using the t test and Levene's test. The results were presented using descriptive statistics.

 Fifty patients with ductal carcinoma were assessed based on their pathological information. The examination of factors including tumor size, involvement/non-involvement of lymph nodes, histological grade, and age of patients revealed a significant direct relationship between tumor size and lymph node involvement (P <0.05), while no significant relationship was found with other mentioned factors.

 The prevalence of ductal breast carcinoma in Iranian women is increasing that may lead to death in many patients. Thus, it is necessary to evaluate this disease. In this study, a significant relationship was found in terms of tumor size and lymph node involvement, which can be effective in early diagnosis and prevention of this type of cancer.