Synthesis of Triphenyl-1H-imidazole Derivatives Using Pectin as a Green Catalyst

A one-pot synthesis of imidazole scaffolds using multi-component reactions as a highly effective methodology is presented. In this three-component reaction with the use of benzyl, aromatic aldehydes, and ammonium acetate in the presence of pectin as a green catalyst, tri-substituted imidazoles in ethanol as a solvent in high yield were prepared. In this reaction, a variety of aromatic aldehydes with electron-withdrawing and electron-donating groups have been used, and the high yields in the final products demonstrate the catalytic performance of pectin in these types of reactions. Some advantages of this method are the use of pectin as a cheap, green, and non-toxic catalyst, as well as the easy separation of products that excludes the use of chromatography for separation, as well as the high purity of the products obtained in this The type of reaction is very important.