Effect of Microwave Irradiation on Synthesis and Behavior of Biphasic Calcium Phosphate in Simulated Body Fluid

Using microwave irradiation in microwave-assisted synthesis method is a new approach employed to decrease synthesis time and to form more homogenous structures of biphasic calcium phosphate bioceramics. In this research, the microwave assisted synthesis and characterization of biphasic calcium phosphate nanopowders have been studied. The phase transformation, chemical components, morphology and particle size were characterized by X-Ray Diffraction (XRD) analysis, Fourier Transform Infrared Spectroscopy (FTIR) and Scanning Electron Microscopy (SEM). The results showed that the use of microwave led to improve crystallinity and the crystallite size increases from 16 nm to 27 nm. Also the amount of hydroxyapatite phase in biphasic calcium phosphate changed in the range of 5% to 17%. The prepared sample was put in Simulated Body Fluid (SBF).The pH of the solution was decreased in the present of beta-tricalcium phosphate showed its biodegradable behavior. Also the nucleation and growth of hydroxyapatite particles on TCP produced by microwave -assisted synthesis method changed to be rod like in SBF solution.