Preparation and Characterization of a New Silver/ Starch – Poly(diphenylsulfonyl phthalate) Nanocomposite and Study of Its Drug Releasing

Today, polymer-based nanocomposites are used in medicine and drug delivery  Non-toxic and environmentally friendly nanocomposites are very important. In this study, new polyester-based nanocomposites were prepared using silver nanoparticles, starch, and poly(diphenylsulfonyl phthalate). The structure and morphology of the new nanocomposite were investigated using FT-IR, XRD, DLS, and FE- SEM. Swelling and drug release of the new nanocomposite were determined based on different amounts of silver nanoparticles. A polymeric alloy of starch and poly(diphenylsulfonyl phthalate) had the highest swelling. Drug loading and release in nanocomposites decreased approximately with the increasing amount of silver nanoparticles.