Modified Screen-Printed Electrodes for Simultaneous Determination of Dopamine and Uric Acid in Serum and Urine Samples

The screen-printed technique is widely used as an efficient tool for electrochemical analysis in the environment, clinical, and food samples. In the present work, we have reported a simple and low-cost protocol for simultaneous determination of dopamine and uric acid using immobilization of Magnetic Core-Shell manganese ferrite NanoParticles (MCSNP) onto Screen-Printed Electrode (SPE). Also, the electroanalytical sensing of dopamine was explored at modified SPEs. The response of the modified electrode is linear in the concentration range 1.0 – 275.0 μM and a date action limit of 0.2 μM was achieved. The proposed method was successfully employed to detect dopamine and uric acid in serum and human urine samples.