Construct of Electrochemical Sensor Using Screen Printed Electrode Modified with MnO2 Nanorods for Determination of Dopamine

Since monitoring of drug metabolism and drug quality control plays an important role in human health, the development of easy, correct, and sensitive methods for the detection of active ingredients is important. Different methods have been developed for measuring dopamine in biological samples. In this study, a Screen Printed Electrode (SPE) modified with manganese dioxide nanorods (MnO2) was used as a simple and high sensitive sensor for detecting and measuring dopamine in real samples. The electrochemical behavior of dopamine at SPE was studied using cyclic voltammetry, differential pulse voltammetry, and chronoamperometry. In addition, by using the differential pulse voltammetry method, the calibration curve was obtained at a concentration range of 1.0-0.900 μm with a detection limit of 0.1 μm.