Effect of sixteen week of regular exercise training on serum levels of aminotransferases and lipid profiles in healthy non-athlete men

Dyslipidemia and liver dysfunction are associated with a sedentary lifestyle. The aim of this study was to investigate the effect of sixteen weeks of exercise on serum levels of aminotransferases and lipid profiles in non-athletes men.

In the present Quasi-experimental research, 150 military personnel from Andimeshk and Dezfoul cities were selected by random sampling method and randomly divided into training and control groups. Exercise was performed for sixteen weeks of functional training in three sessions per week. Each training session is approximately 60-90 minutes of training consist of 3-6 sets with 6-9 workout stations with resistance, power and Functional training,  for the upper body, the torso and lower body. Paired sample t-test and independent t-test were used to analyze the data.

After the training period, there was founded a significant decrease in serum levels of ALT (P = 0.005) and AST (P = 0.034) enzymes and a significant increase in serum HDL (P = 0.003). Also, changes in ALT (P < 0.001), AST (P < 0.001), and HDL (P = 0.002) were significant in the exercise group compared to the control group.

Based on the findings of the present study, it can be said that functional training have been able to prevent lipid accumulation in liver tissue by improving lipid profile and had effective on liver function and health due to decreased serum ALT and AST levels as biomarkers related to liver function.