Evaluation of Association between duration of Hospital-ization in-Patient with Deep Venous Thrombosis and thetype of Treatment Considering the Effect of Comorbid Dis-eases

Deep vein thrombosis (DVT) is a common disease with serious risks such as pulmonary embolismand there are different anticoagulant therapies for treatment of this condition. In this study, we investigatedthe association between the duration of hospitalization with different treatment methods and comorbidities.

In this retrospective cross-sectional study, the hospital records of 213 patients with adiagnosis of acute DVT in Shohada-e-Tajrish Hospital in 2019 and 2020 were reviewed. Patients were dividedinto five main groups and five subgroups based on the type of treatment. Then, the association between theduration of hospitalization and different treatment methods was studied.

Treatment with novel oralanticoagulants (NOACs) with an average length of 2.5 days of hospitalization significantly reduces the durationof hospitalization. Combination therapy with low molecular weight heparin (LMWH) and warfarin or LMWHalone, with an average of 8.38 and 8.20 days, is preferable to treatment with unfractionated heparin (UFH) andwarfarin, with an average of 9.2 days. Warfarin treatment with an average duration of hospitalization of 8.43days is in the third place. The use of other methods has increased the duration of hospitalization. History ofcomorbidities including history of hospitalization, hypertension, smoking, cancer and trauma are the five co-morbidities that have the greatest effect on the length of hospitalization of patients, respectively.

According to the present study, treatment with NOACs reduces the duration of hospitalization of patients morethan the other treatment methods. The second best choice is LMWH injection therapy and continuation withwarfarin or starting and continuing treatment with LMWH preferable to injecting treatment with UFH and con-tinuing with warfarin. The type of underlying disease and comorbidities had a significant effect on the durationof hospitalization.