Case Report of Encephalopathy in Goats

Polioencephalomalacia is none infectious neuro degenerative disease that affect sheep, goat, deer and cow. Polioencephalomalacia commonly occur in cattle fed ration rich in carbohydrates with \ittle roughage that may changes microflora of rumen and impaired synthesize of thiamine (Thomson et 0/200 1, Boyd & Walton 1977). Polioencephalomalacia could represent a multifactoral metabolic disorder with multiple etiologies such as nutritional problem, high level of carbohydrate, water deprivation, salt intoxication, high level intake of sulfur, renal encephalopathy, amprolium and sorne plant such as Bracken fem and Horsetail. Probable mechanisms that may cause thiamine deficiency polioencephalomalacia in ruminant are disorder of absorption, synthesize and destruction of thiamine by thiaminase (Radostit et al 1994, Bakker et 0/1980, Jeffrey et 0/1994, Loew & Dunlop 1972, Olkowski 1992, Thomber et al 1979). Evidence (or theories) linking thiamine with the ruminant polioencephalomalacia disorder incIude cIinical response to thiamine injection in sorne individual (Thomson et 012001).