Baneh Fruits (Pistacia Atlantica) improved Some Biochemical Parameters in Wistar Male Rats

In traditional medicines, almost all Asian countries, particularly Iran, consider plants for therputical purposes. This study assessed the impact of the Baneh Fruits (Pistacia Atlantica) hydroethanolic extract on certain enzymes and biochemical elements in rats.

200 and 400 mg/kg of the extract were given orally once a day for 28 days to two rat groups, each with eight animals. The control group was given only distilled water. Under chloroform anesthesia, the rats fasted overnight were dissected on the 29th day. Then, their blood was directly taken from their hearts. In the next step, some liver biochemical parameters including aspartate aminotransferase (AST), alanine aminotransferase (ALT), gamma-glutamyl transferase (GGT), total bilirubin, biochemical parameters of kidney including blood urea nitrogen (BUN), creatinine, urea, and metabolic parameters including fasting plasma glucose (FPG), cholesterol, triglycerides, and high-density lipoprotein cholesterol (HDL-C) were measured in the collected blood serums.

The plant fruit extract decreased significantly the serum concentrations of triglycerides, cholesterol, AST, creatinine, and total bilirubin in the two doses (p<0.05). The 200 mg/kg dose decreased BUN and urea concentrations and increased HDL-C concentration significantly (p<0.05). While only a dose of 400mg/kg of the extract decreased the GGT level significantly (p<0.05).

The hypocholesterolemic, hypotriglyceridemic, and hypo bilirubinemic impact of the extract coupled with the decreased AST activity indicated that the Baneh fruit may be beneficial in controlling hypertriglyceridemia and hyper-cholesterolemia.