The effects of 4-week of detraining on metabolic syndrome and run time to exhaustion in overweight trained men

Training-induced metabolic adaptations reduce in response to detraining, but data is limited to the comparison of the effects of detraining followed different types of training. Thus, the purpose of this study was to determine the effects of 4-week of detraining on metabolic syndrome and run time to exhaustion (TTE) in the resistance-trained men and the aerobic-trained men.

In the quasi-experimental study, 19 men (25-38 years) who are trained were assigned into resistance-trained (RT, n = 10) and aerobic-trained (AT, n = 9) groups. The groups were matched by the physical activity levels during the past 4 months (three days a week with moderate intensity), age, and body mass index (25-29.9 kg/m2). All subjects avoided performing any exercise for a month. From all subjects, the blood sample was taken in a fasted state to measure serum glucose, insulin triglyceride, and high-density lipoprotein cholesterol (HDL-C) levels before and after the detraining. The TTE measured at vVO2max intensity on a treadmill in these time points. Insulin resistance index estimated using by HOMA-IR method. 

After the detraining period, TTE and HDL-C decreased significantly in both groups; however, triglyceride was significantly increased (all variables, P < 0.05).There was a significant increase in insulin levels with RT only (P = 0.02). There were no significant differences in insulin resistance index and glucose in these groups. 

It seems like that the detraining-induced negative effects are similar to the aerobic fitness and most of the metabolic syndrome in these groups. However, the negative effect of the detraining was higher in RT (as increased by insulin) compared to AT.