The effect of 12 weeks selective combined training on plasma acylated ghrelin and lipid profile in overweight females

The aim of this study was to investigate the effect of 12 weeks combined training on plasma acylated ghrelin and lipid profile in overweight females.

40 non-athlete overweight females (BMI=25-30) were randomly selected from more than 400 eligible students of Varamin Azad university and randomly divided in two experimental and control groups. Training protocol lasted for 12 weeks and included seven sessions per week. Four sessions consisted of interval endurance training with the intensity of 55-75% of maximum heart rate. Two Sessions per week were assigned to circuit progressive resistance training at 50-60% 1RM. One session per week was also allocated to handball training with the same intensity of endurance training. Blood samples were taken in fasting state from all subjects, before and 72 hours after interventions. Plasma ghrelin amount was determined by ELISA test, HDL was evaluated using colorimetric method, and triglyceride and total cholesterol were determined by Enzymatic Photometric method. The statistical analysis of research was done by Repeated measures ANOVA at the significance level of P

According to the results, significant increases in plasma ghrelin (P=0.029) and HDL cholesterol (P=0.011), and significant decreases in total cholesterol (P=0.039), triglyceride (P=0.047) and LDL cholesterol (P=0.038) in experimental group were seen, while the changes in control group were not significant.

These results highlighted the effective role of selective combined training on simultaneously increasing ghrelin hormone and improving lipid profile. Generally, these results showed the advantages of selected protocol training on improving metabolic status in overweight individuals.