Epidemiological investigation of salmonella enterica isolates in children with diarrhea in chengdu, China

Background：

It is easy for salmonella to infect children through fecal-oral route and cause diarrhea. The analysis of pathogen distribution and epidemic characteristics of such infectious diseases has become a major topic for national research, providing direction and guidance for national prevention policy.

To study epidemiologyof enterical salmonella in children with diarrhea.

Pediatricians screened suspected cases of Salmonella, and stool specimens were cultured, identified, and serotyped.

A total of 649 salmonella strains were isolated from 6656 children with suspected salmonella infection. The NTS isolation rate was 8.92%, and the S.typhi isolation rate was 0.83%.A total of 19 serotypes were isolated, and the first five serotypes were Salmonella typhimurium, paratyphoid, Dublin, typhoid and London. The positive rates of the five serotypes were 90.29%, and the positive rates of Salmonella typhimurium and Enteritis were 74.88% and 1.08%, respectively. The infection of Salmonella increased with time. The positive rates of typhoid, paratyphoid A, paratyphoid B and paratyphoid C were 4.16%, 0.3%, 3.0% and 0.9%, respectively. Boys: girls = 1.30:1,There was no significant difference in gender of salmonella infection.The infection rate was lowest between 1 day and 6 months (P< 0.05), salmonella mainly infected children under 3 years old, and the positive rate was 88.29%.In the warm and humid summer and autumn season (June to September), the infection rate of Salmonella was the highest, with a positive rate of 72.73%.

The infection rate of salmonella in children under 3 years old was the highest, and the incidence of salmonella in children with diarrhea was increasing in Chengdu. Typhoid and paratyphoid vaccines should be considered together, and vaccines should focus on children under 3 years of age.