The Assessment of Association between Uterine Artery Pulsatility Index at 30–34 Week’s Gestation and Adverse Perinatal Outcome

Given the high prevalence of adverse perinatal outcome in the developing countries and the association between uterine artery (UtA) blood fl ow and fetal status in the uterine, in the current study, we assess the association between UtA pulsatility index (UtA-PI) at 30–34 week’s gestation and adverse perinatal outcome.

This cohort study included 100 pregnant women at 30–34 weeks’ gestation. At baseline, UtA-PI was evaluated with color Doppler through abdominal ultrasound. Then, adverse perinatal outcomes including preterm labor, intrauterine fetal death, preeclampsia, low 5-min Apgar score (<7), low umbilical arterial cord blood pH, admitted to Intensive Care Unit in the fi rst 3 days of birth, low birth weight, infant with low weight, death of newborns, cesarean section for respiratory distress, and meconial amniotic fl uid were recorded. Ultimately, the collected data were analyzed using SPSS, version 20.

The presence of small-for-gestational-age fetuses indicated the highest prevalent adverse prenatal outcome with the incidence of 13.3% and 58.5%, respectively, among pregnancies with normal UtA-PI as well as those with high UtA-PI (P < 0.001). Overall, given that sensitivity and specifi city of high UtA-PI were 37.5% and 73.3%, respectively, it could not properly predict adverse perinatal outcome (P = 0.360).

According to the results, although the incidence of some of adverse perinatal outcomes in pregnant women with high UtA-PI was higher compared to those with normal UtA-PI, this factor alone cannot predict adverse perinatal outcome well. Therefore, this factor may predict these outcomes well, in the subgroups with high-risk pregnancies or with some blood factors or with pregnancy complications.