Synthesis of Some Arylidene Heterobicyclic Compounds using Nano Al2O3-SO3H under Sonication Conditions

The condensation of aromatic aldehydes, cyclopentanone and urea promoted by nano Al2O3-SO3H and HCl (aq) as heterogeneous and homogeneous catalysts, respectively, have been developed for the  synthesis  of  some  arylidene  heterobicyclic  compounds.  In  this  synthesis,  we  have  used  two methods with sonication and thermal condition that have several advantages such as excellent yields and  short  reaction  times. The  ultrasonic  device  used  in  this  study includes  an  ultrasonic  bath equipped with a thermal system designed and built in our laboratory.